Protein Based Vaccines

Some vaccines, instead of being generated from the whole cell, are made only from TAA proteins, or even small fragment of TAA proteins called TAA-derived peptides. Those peptides contain epitopes which can present by MHC molecules in the cell surface and recognized by T cells as target tumor antigen. The Peptide-based vaccines take the advantage of the ability of computer algorithms to screen protein amino acids sequences for peptide epitopes derived from TAAs.