Breakthroughs in next-generation vaccine technologies are reshaping immunization with unprecedented speed and precision. Self-amplifying RNA, circular RNA, viral replicons, and nanoparticle-based carriers are pushing the boundaries of immune engineering. These platforms offer benefits like dose sparing, rapid development, thermostability, and targeted delivery. Researchers are also exploring microneedle patches, oral formulations, and implantable devices to improve accessibility and compliance. Integration with AI-driven antigen design and immunoinformatics accelerates the transition from concept to clinic. Next-generation vaccine technologies are particularly promising for rapidly mutating pathogens and individualized immunotherapies. Their success depends on interdisciplinary collaboration across material science, molecular biology, and digital health. As innovation accelerates, these technologies stand to revolutionize global vaccine development and distribution.
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Title : Personalized and Precision Medicine (PPM) via biodesign-driven translational applications and upgraded business modeling to secure the human biosafety: The next-step vaccinomics of the future
Sergey V Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Title : The promise of nanotechnology in Personalized & Precision Medicine: Nano-driven precision vaccinomics of the future
Sergey V Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Title : Recombinant BCG vaccine as a potent anti tuberculosis vaccine candidate
Sajal Dey, BRIC-Centre for DNA Fingerprinting and Diagnostics, India
Title : Emerging nanovaccine strategies for enhanced immune targeting and vaccine performance
Aysel Sadayli, V.Y. Axundov Scientific-Research Institute of Medical Prophylaxis, Azerbaijan
Title : Advancing vaccine availability and equity in low-resource settings: Evidence from Awendo Sub-County, Kenya
Millicent Ochieng, Clinton Health Access Initiative, Kenya
Title : Reaching zero-dose children through adaptive immunization strategies in security-compromised areas of Zamfara State, Nigeria
Attahir Abubakar, Ahmadu Bello University, Nigeria
Title : From local pilots to national policy: Key issues and challenges in implementing nationwide HPV vaccination in China
Shenglan Tang, Duke Global Health Institute, United States