Enhancing immunogenicity without compromising safety is a central goal in modern immunoprophylaxis, and vaccine adjuvants and immunomodulators play a pivotal role in achieving it. These agents stimulate, direct, or modulate the immune response to improve vaccine efficacy, particularly in populations with weaker immunity such as the elderly or immunocompromised. From aluminum salts to saponin-based formulations and Toll-like receptor agonists, the landscape of adjuvants is expanding rapidly. Immunomodulators further fine-tune responses by influencing cytokine profiles, antigen presentation, and T-cell polarization. Beyond boosting responses, they contribute to dose sparing and cross-protection against antigenic variants. Safety profiling, compatibility with different antigen types, and long-term immunological outcomes remain critical aspects of ongoing research. As global attention shifts toward adaptable platforms, Vaccine adjuvants and immunomodulators are becoming integral to the success of next-generation vaccines addressing complex and evolving disease threats.
Khursheed Anwer
IMUNON, United States
Ping Xie
Rutgers University, United States
Regina Au
BioMarketing Insight, United States
Madhu Khanna
University of Delhi, India
Lara Isis Teodoro
Mayo Clinic, United States
Ahmed Abdulazeez
BHRUT Trust, United Kingdom
Elena Chiappini
University of Florence, Italy
Ayesha Zahid
Griffith University, Australia
Livia Daflon Silva
Federal University of State of Rio de Janeiro, Brazil
Neha Bhandari
Chitkara University, IndiaSubmit your abstract Today
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