With their rapid development and scalable design, mRNA and DNA-based vaccines have reshaped the field of vaccinology. These nucleic acid platforms instruct cells to produce antigenic proteins, prompting strong immune responses without using live pathogens. Their flexibility allows quick updates for evolving threats, as seen with COVID-19 vaccines. Delivery systems like lipid nanoparticles and electroporation are continuously improving their stability and efficacy. Safety profiles, low production costs, and adaptability make these vaccines attractive for global deployment. As research expands into oncology and rare diseases, mRNA and DNA-Based Vaccines are establishing themselves as pivotal technologies in both preventive and therapeutic settings.
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Title : Emerging nanovaccine strategies for enhanced immune targeting and vaccine performance
Aysel Sadayli, V.Y. Axundov Scientific-Research Institute of Medical Prophylaxis, Azerbaijan
Title : Reaching zero-dose children through adaptive immunization strategies in security-compromised areas of Zamfara State, Nigeria
Attahir Abubakar, Ahmadu Bello University, Nigeria
Title : Advancing vaccine availability and equity in low-resource settings: Evidence from Awendo Sub-County, Kenya
Millicent Ochieng, Clinton Health Access Initiative, Kenya