Reverse vaccinology and immunoinformatics are transforming vaccine discovery through computational modeling and genome analysis. Unlike traditional approaches, reverse vaccinology begins with genome mining to identify potential antigens without culturing the pathogen. This is followed by in silico prediction of epitope structure, antigenicity, and population coverage. Immunoinformatics tools analyze immune system interactions, helping refine candidate selection and optimize delivery. This data-driven approach accelerates development timelines and lowers costs, especially for complex or emerging pathogens. Reverse vaccinology and immunoinformatics are enabling rapid responses to outbreaks, personalized vaccine strategies, and multivalent designs. As bioinformatics capabilities expand, these methodologies are becoming integral to modern vaccinology and global health innovation.
Title : A promising novel approach to DNA vaccines
Khursheed Nadeem Anwer, IMUNON, United States
Title : Nanoscopic SubATVax™ adjuvanted vaccines against influenza A types H3N2, H1N1 and influenza type B for subcutaneous administration
David Craig Wright, D4 Labs, LLC, United States
Title : The importance of post-marketing surveillance and real-world data for a product to be successful
Regina Au, BioMarketing Insight, United States
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : Commensal bacteria drive B-cell lymphomagenesis in the setting of innate immunodeficiency
Ping Xie, Rutgers University, United States
Title : The role of immunity in the pathogenesis of SARS-COV-2 and in the protection generated by COVID-19 in different age groups
Ahmed Abdulazeez, BHRUT Trust, United Kingdom
Title : Establishing a platform method for physical appearance assessment of new parenteral pharmaceuticals
Ying Wan, Merck & Co., United States
Title : Evaluating the immunogenic impact of process impurities in mRNA vaccine production: Establishing integrated control strategies and specifications
Jesse Kuiper, Merck Research Laboratories, United States
Title : New biomarkers in leishmania major vaccine development
Negar Seyed, Pasteur Institute of Iran, Iran (Islamic Republic of)
Title : Advances in vaccines: Revolutionizing disease prevention
Delia Teresa Sponza, Dokuz Eylul University, Turkey