Understanding how immunizations stimulate protection begins with a deep dive into the mechanisms of vaccine action & immune response. Cellular and humoral components interact in finely tuned sequences, with antigen presentation, cytokine signaling, and T and B cell activation forming the foundation of long-term immunity. These mechanisms vary depending on the nature of the vaccine platform and the immune status of the recipient. Research now extends beyond classical pathways, incorporating innate immune training, epigenetic reprogramming, and memory imprinting. A more nuanced grasp of these biological processes enables the design of next-generation vaccines that are both targeted and durable. Ongoing investigations also explore how variations in host genetics, microbiota, and previous exposures affect immunologic outcomes. Clarifying these relationships is key to addressing population-level variability in vaccine efficacy and safety, ultimately guiding more personalized and effective immunization strategies.
Title : A promising novel approach to DNA vaccines
Khursheed Anwer, IMUNON, United States
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : The importance of post-marketing surveillance and real-world data: For a product to be successful
Regina Au, BioMarketing Insight, United States
Title : Development of a novel multi-component vaccine to address the burden of otitis media in high-risk populations
Ayesha Zahid, Griffith University, Australia
Title : New biomarkers in leishmania major vaccine development
Negar Seyed, Pasteur Institute of Iran, Iran (Islamic Republic of)
Title : Approaches towards developing and establishing a biomanufacturing research & development, and manufacturing industry in Zimbabwe: A review of the need, potential funding sources, policy development and implementation
Elliot Nyagumbo, Midlands State University, Zimbabwe
Title : Evaluating the immunogenic impact of process impurities in mRNA vaccine production: Establishing integrated control strategies and specifications
Jesse Kuiper, Merck Research Laboratories, United States
Title : Capillary electrophoresis for adjuvanted multivalent recombinant vaccine purity determination
Ashley Prout, Merck, United States
Title : Hypersensitivity and anti-SARS-COV-2 vaccination: A retrospective study of the year 2021 at the University Hospital Center of Tours (France)
Faure Quentin, The Savoie Metropolitan Hospital Center, France
Title : THE HPV vaccination program in Colombia. From a beautiful dream to a nightmare, but hopefully with a bright dawn.
Carlos Castro, Colombian League against cancer, Colombia