One of the key advancements in Next-Generation Antibodies is the use of recombinant DNA technology to produce monoclonal antibodies with improved properties. By manipulating the genes encoding antibody molecules, scientists can engineer antibodies with enhanced potency, stability, and specificity. Next-generation antibodies can be designed to target specific components of pathogens, such as viral proteins or bacterial toxins, with high precision. This targeted approach allows for the development of vaccines and immunotherapies that are highly effective at preventing or treating infections.
In addition to their use in vaccines, next-generation antibodies hold promise for the treatment of cancer. Antibody-based therapies, such as immune checkpoint inhibitors and antibody-drug conjugates, are already revolutionizing cancer treatment by targeting cancer cells while sparing healthy cells. Furthermore, next-generation antibodies can be engineered to modulate the immune system and regulate immune responses in autoimmune disorders and inflammatory diseases. By targeting specific immune cells or cytokines involved in the disease process, these antibodies offer new therapeutic options for patients with conditions such as rheumatoid arthritis, multiple sclerosis, and inflammatory bowel disease.
Advancements in antibody engineering techniques, such as phage display, yeast display, and computational design, are driving innovation in the field of next-generation antibodies. These techniques allow researchers to screen large libraries of antibody variants and select molecules with desired properties, such as high affinity, specificity, and stability.
Title : Tubercular disease in children: Optimizing treatment strategies through disease insights
Elena Chiappini, University of Florence, Italy
Title : Prophylactic and Molecular Approaches for Mitigating Human Influenza A Viruses: i. Evaluating influenza Vaccine Effectiveness in the Older population ii. Down-regulation of influenza virus genes with novel siRNA-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : The role of immunity in the pathogenesis of SARS-COV-2 and in the protection generated by COVID-19 in different age groups
Ahmed Abdulazeez, BHRUT Trust, United Kingdom
Title : Development of a Novel Multi-component Vaccine to Address the Burden of Otitis Media in High-Risk Populations
Ayesha Zahid, Griffith University, Australia
Title : Targeting resistance: New 4-substituted pyrazolidine and isoxazolidine as antibiotics with interesting antimicrobial activities
Yousfi Tarek, Nationale Research for Biotechnology Research Center, Algeria
Title : Racial disparities in pediatric pneumonia in Brazil: The role of structural racism forging inequalities in acess to vaccines
Livia Daflon Silva, Federal University of State of Rio de Janeiro, Brazil
Title : Immunosuppression in COVID-19 Patients and Emerging Fungal Infections: Vaccines, Diagnosis and Strategies to Treat Comorbidities
K R Aneja, Kurukshetra University, India
Title : Immunogenicity and Cryo-EM structure of native-like HIV-1 Clade-C envelope trimers derived from a pediatric elite-neutralizer
Swarandeep Singh, All India Institute of Medical Sciences, India
Title : Why is the vaccine life-threatening if people get a fever after a COVID-19 vaccination
Yacob Mathai, Marma Health Centre, India
Title : Barriers to polio eradication in South Asia: A systematic review
Awranoos Ahadi, Bolan Medical College, Pakistan