One of the key advancements in Next-Generation Antibodies is the use of recombinant DNA technology to produce monoclonal antibodies with improved properties. By manipulating the genes encoding antibody molecules, scientists can engineer antibodies with enhanced potency, stability, and specificity. Next-generation antibodies can be designed to target specific components of pathogens, such as viral proteins or bacterial toxins, with high precision. This targeted approach allows for the development of vaccines and immunotherapies that are highly effective at preventing or treating infections.
In addition to their use in vaccines, next-generation antibodies hold promise for the treatment of cancer. Antibody-based therapies, such as immune checkpoint inhibitors and antibody-drug conjugates, are already revolutionizing cancer treatment by targeting cancer cells while sparing healthy cells. Furthermore, next-generation antibodies can be engineered to modulate the immune system and regulate immune responses in autoimmune disorders and inflammatory diseases. By targeting specific immune cells or cytokines involved in the disease process, these antibodies offer new therapeutic options for patients with conditions such as rheumatoid arthritis, multiple sclerosis, and inflammatory bowel disease.
Advancements in antibody engineering techniques, such as phage display, yeast display, and computational design, are driving innovation in the field of next-generation antibodies. These techniques allow researchers to screen large libraries of antibody variants and select molecules with desired properties, such as high affinity, specificity, and stability.
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : Homology analysis of MPXV and VACV peptides underscores the need to consider both MPXV clades for vaccine development
Lara Isis Teodoro, Mayo Clinic, United States
Title : Development of a novel multi-component vaccine to address the burden of otitis media in high-risk populations
Ayesha Zahid, Griffith University, Australia
Title : High seroprevalence of RSV antibodies in adults indicates potential undetected transmission and requires further public health assessment
Lara Isis Teodoro, Mayo Clinic, United States
Title : The role of immunity in the pathogenesis of SARS-COV-2 and in the protection generated by COVID-19 in different age groups
Ahmed Abdulazeez, BHRUT Trust, United Kingdom
Title : New biomarkers in leishmania major vaccine development
Negar Seyed, Pasteur Institute of Iran, Iran (Islamic Republic of)
Title : Tubercular disease in children: Optimizing treatment strategies through disease insights
Elena Chiappini, University of Florence, Italy
Title : Approaches towards developing and establishing a biomanufacturing research & development, and manufacturing industry in Zimbabwe: A review of the need, potential funding sources, policy development and implementation
Elliot Nyagumbo, Midlands State University, Zimbabwe
Title : Racial disparities in pediatric pneumonia in Brazil: The role of structural racism forging inequalities in acess to vaccines
Livia Daflon Silva, Federal University of State of Rio de Janeiro, Brazil
Title : Capillary electrophoresis for adjuvanted multivalent recombinant vaccine purity determination
Ashley Prout, Merck, United States