One of the key advancements in Next-Generation Antibodies is the use of recombinant DNA technology to produce monoclonal antibodies with improved properties. By manipulating the genes encoding antibody molecules, scientists can engineer antibodies with enhanced potency, stability, and specificity. Next-generation antibodies can be designed to target specific components of pathogens, such as viral proteins or bacterial toxins, with high precision. This targeted approach allows for the development of vaccines and immunotherapies that are highly effective at preventing or treating infections.
In addition to their use in vaccines, next-generation antibodies hold promise for the treatment of cancer. Antibody-based therapies, such as immune checkpoint inhibitors and antibody-drug conjugates, are already revolutionizing cancer treatment by targeting cancer cells while sparing healthy cells. Furthermore, next-generation antibodies can be engineered to modulate the immune system and regulate immune responses in autoimmune disorders and inflammatory diseases. By targeting specific immune cells or cytokines involved in the disease process, these antibodies offer new therapeutic options for patients with conditions such as rheumatoid arthritis, multiple sclerosis, and inflammatory bowel disease.
Advancements in antibody engineering techniques, such as phage display, yeast display, and computational design, are driving innovation in the field of next-generation antibodies. These techniques allow researchers to screen large libraries of antibody variants and select molecules with desired properties, such as high affinity, specificity, and stability.
Title : The importance of post-marketing surveillance and real-world data: For a product to be successful
Regina Au, BioMarketing Insight, United States
Title : A promising novel approach to DNA vaccines
Khursheed Anwer, IMUNON, United States
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : Post COVID-19 syndrome is associated with sex and severity of first COVID-19 episode in Honduras
Manuel Antonio Sierra Santos, Central American Technological University, Honduras
Title : Homology analysis of MPXV and VACV peptides underscores the need to consider both MPXV clades for vaccine development
Lara Isis Teodoro, Mayo Clinic, United States
Title : High seroprevalence of RSV antibodies in adults indicates potential undetected transmission and requires further public health assessment
Lara Isis Teodoro, Mayo Clinic, United States
Title : Establishing a platform method for physical appearance assessment of new parenteral pharmaceuticals
Ying Wan, Merck & Co., United States
Title : Development of a novel multi-component vaccine to address the burden of otitis media in high-risk populations
Ayesha Zahid, Griffith University, Australia
Title : Development of a platform UPLC-CAD method for high-throughput lipid quantitation and characterization in novel mRNA LNPs
Janet Muzulu, Sanofi, United States
Title : The role of immunity in the pathogenesis of SARS-COV-2 and in the protection generated by COVID-19 in different age groups
Ahmed Abdulazeez, BHRUT Trust, United Kingdom