Neoantigens are unique molecules produced by mutated genes in cancer cells or infected cells that are not present in normal cells. These antigens serve as potential targets for the immune system and are key to developing personalized vaccines. Neoantigen vaccines are designed to identify and target these mutated proteins, stimulating the immune system to recognize and destroy cancer cells or infected cells that harbor these mutations. The beauty of neoantigen-based vaccines lies in their ability to generate highly specific immune responses, as the antigens are unique to the tumor or pathogen, minimizing the risk of off-target effects. This approach has shown promise in cancer immunotherapy, offering potential treatments for cancers that are otherwise difficult to treat. By tailoring vaccines to an individual’s specific neoantigens, researchers can develop personalized therapies that enhance immune surveillance and improve the effectiveness of treatments for both cancer and infectious diseases.
Title : The importance of post-marketing surveillance and real-world data for a product to be successful
Regina Au, BioMarketing Insight, United States
Title : Nanoscopic SubATVax™ adjuvanted vaccines against influenza A types H3N2, H1N1 and influenza type B for subcutaneous administration
David Craig Wright, D4 Labs, LLC, United States
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : A promising novel approach to DNA vaccines
Khursheed Nadeem Anwer, IMUNON, United States
Title : The role of immunity in the pathogenesis of SARS-COV-2 and in the protection generated by COVID-19 in different age groups
Ahmed Abdulazeez, BHRUT Trust, United Kingdom
Title : Establishing a platform method for physical appearance assessment of new parenteral pharmaceuticals
Ying Wan, Merck & Co., United States
Title : Advances in vaccines: Revolutionizing disease prevention
Delia Teresa Sponza, Dokuz Eylul University, Turkey
Title : Overcoming biophysical characterization challenges of small antigens in dilute vaccine formulations
Eric Kemp, Merck & Co., United States
Title : Commensal bacteria drive B-cell lymphomagenesis in the setting of innate immunodeficiency
Ping Xie, Rutgers University, United States
Title : A combined LC-MS and immunoassay approach to characterize preservative-induced destabilization of human papillomavirus virus-like particles adsorbed to an aluminum-salt adjuvant
Ria T Caringal, University of Kansas, United States