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Mycobacterium Bovis

Mycobacterium bovis is a bacterium belonging to the Mycobacterium tuberculosis complex, known for causing bovine tuberculosis in cattle. This pathogen can also infect a wide range of mammals, including humans, leading to zoonotic transmission. Bovine tuberculosis poses a significant threat to livestock industries and has public health implications due to the potential transmission to humans through consumption of contaminated dairy products or direct contact with infected animals. In humans, M. bovis infection can result in pulmonary and extrapulmonary tuberculosis. Control measures for M. bovis include testing and culling infected animals, pasteurization of milk to reduce transmission through dairy products, and vaccination programs in some regions. The Bacillus Calmette-Guérin (BCG) vaccine, initially developed to protect against Mycobacterium tuberculosis, also provides partial protection against M. bovis. M. bovis has a complex genome, and understanding its virulence factors and mechanisms of transmission is essential for developing effective control strategies. Ongoing research focuses on improving diagnostic tools, vaccines, and management practices to mitigate the impact of M. bovis on both animal and human health.

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