Viral replication is a complex process by which viruses use host cell machinery to produce new viral particles. The life cycle generally involves several key stages: attachment, penetration, uncoating, replication and transcription, translation, assembly, and release. Upon attaching to specific host cell receptors, viruses penetrate the cell either through direct fusion with the cell membrane or via endocytosis. Once inside, the virus undergoes uncoating, freeing its genetic material. Replication and transcription involve the synthesis of viral RNA or DNA using host cell machinery. Viral proteins are then produced through translation of the viral genome. These components are assembled into new virus particles, often in specialized cellular compartments. Release can occur through cell lysis, where the host cell is destroyed, or through a more subtle process called budding, where new virus particles exit the cell without causing immediate cell death. Understanding viral replication is crucial for developing antiviral strategies, including drugs that target various stages of the viral life cycle. Research in this area continues to uncover the intricacies of host-virus interactions, aiding the development of interventions to combat viral infections.
Title : A promising novel approach to DNA vaccines
Khursheed Anwer, IMUNON, United States
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : The importance of post-marketing surveillance and real-world data: For a product to be successful
Regina Au, BioMarketing Insight, United States
Title : Development of a novel multi-component vaccine to address the burden of otitis media in high-risk populations
Ayesha Zahid, Griffith University, Australia
Title : New biomarkers in leishmania major vaccine development
Negar Seyed, Pasteur Institute of Iran, Iran (Islamic Republic of)
Title : Approaches towards developing and establishing a biomanufacturing research & development, and manufacturing industry in Zimbabwe: A review of the need, potential funding sources, policy development and implementation
Elliot Nyagumbo, Midlands State University, Zimbabwe
Title : Evaluating the immunogenic impact of process impurities in mRNA vaccine production: Establishing integrated control strategies and specifications
Jesse Kuiper, Merck Research Laboratories, United States
Title : Capillary electrophoresis for adjuvanted multivalent recombinant vaccine purity determination
Ashley Prout, Merck, United States
Title : Hypersensitivity and anti-SARS-COV-2 vaccination: A retrospective study of the year 2021 at the University Hospital Center of Tours (France)
Faure Quentin, The Savoie Metropolitan Hospital Center, France
Title : THE HPV vaccination program in Colombia. From a beautiful dream to a nightmare, but hopefully with a bright dawn.
Carlos Castro, Colombian League against cancer, Colombia