Viral replication is a complex process by which viruses use host cell machinery to produce new viral particles. The life cycle generally involves several key stages: attachment, penetration, uncoating, replication and transcription, translation, assembly, and release. Upon attaching to specific host cell receptors, viruses penetrate the cell either through direct fusion with the cell membrane or via endocytosis. Once inside, the virus undergoes uncoating, freeing its genetic material. Replication and transcription involve the synthesis of viral RNA or DNA using host cell machinery. Viral proteins are then produced through translation of the viral genome. These components are assembled into new virus particles, often in specialized cellular compartments. Release can occur through cell lysis, where the host cell is destroyed, or through a more subtle process called budding, where new virus particles exit the cell without causing immediate cell death. Understanding viral replication is crucial for developing antiviral strategies, including drugs that target various stages of the viral life cycle. Research in this area continues to uncover the intricacies of host-virus interactions, aiding the development of interventions to combat viral infections.
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Title : Tubercular disease in children: Optimizing treatment strategies through disease insights
Elena Chiappini, University of Florence, Italy
Title : Prophylactic and Molecular Approaches for Mitigating Human Influenza A Viruses: i. Evaluating influenza Vaccine Effectiveness in the Older population ii. Down-regulation of influenza virus genes with novel siRNA-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : The role of immunity in the pathogenesis of SARS-COV-2 and in the protection generated by COVID-19 in different age groups
Ahmed Abdulazeez, BHRUT Trust, United Kingdom
Title : Development of a Novel Multi-component Vaccine to Address the Burden of Otitis Media in High-Risk Populations
Ayesha Zahid, Griffith University, Australia
Title : Targeting resistance: New 4-substituted pyrazolidine and isoxazolidine as antibiotics with interesting antimicrobial activities
Yousfi Tarek, Nationale Research for Biotechnology Research Center, Algeria
Title : Racial disparities in pediatric pneumonia in Brazil: The role of structural racism forging inequalities in acess to vaccines
Livia Daflon Silva, Federal University of State of Rio de Janeiro, Brazil
Title : Immunosuppression in COVID-19 Patients and Emerging Fungal Infections: Vaccines, Diagnosis and Strategies to Treat Comorbidities
K R Aneja, Kurukshetra University, India
Title : Immunogenicity and Cryo-EM structure of native-like HIV-1 Clade-C envelope trimers derived from a pediatric elite-neutralizer
Swarandeep Singh, All India Institute of Medical Sciences, India
Title : Why is the vaccine life-threatening if people get a fever after a COVID-19 vaccination
Yacob Mathai, Marma Health Centre, India
Title : Barriers to polio eradication in South Asia: A systematic review
Awranoos Ahadi, Bolan Medical College, Pakistan