Viral gene evolution is a dynamic process characterized by the continuous adaptation and modification of viral genetic material over time. This phenomenon is driven by several factors, including natural selection, genetic mutations, and recombination events, resulting in the diversity of viral populations. Mutations in viral genes occur as a natural consequence of viral replication, with some mutations conferring advantages, disadvantages, or neutral effects on viral fitness. Positive selection favors mutations that enhance viral replication, transmission, or evasion of host immune responses. Recombination, where genetic material from different viruses combines, further contributes to viral gene evolution. This process can lead to the emergence of novel viral strains with unique genetic compositions and potentially altered biological properties. Selective pressures, such as host immune responses and antiviral interventions, play a crucial role in shaping viral gene evolution. Rapid evolution allows viruses to evade immune recognition and develop resistance to antiviral drugs. Understanding viral gene evolution is essential for designing effective vaccines and antiviral strategies. Ongoing research explores the molecular mechanisms driving viral evolution, aiding in the prediction of emerging viral threats and the development of targeted interventions to mitigate their impact.
Title : Tubercular disease in children: Optimizing treatment strategies through disease insights
Elena Chiappini, University of Florence, Italy
Title : Prophylactic and Molecular Approaches for Mitigating Human Influenza A Viruses: i. Evaluating influenza Vaccine Effectiveness in the Older population ii. Down-regulation of influenza virus genes with novel siRNA-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : The role of immunity in the pathogenesis of SARS-COV-2 and in the protection generated by COVID-19 in different age groups
Ahmed Abdulazeez, BHRUT Trust, United Kingdom
Title : Development of a Novel Multi-component Vaccine to Address the Burden of Otitis Media in High-Risk Populations
Ayesha Zahid, Griffith University, Australia
Title : Targeting resistance: New 4-substituted pyrazolidine and isoxazolidine as antibiotics with interesting antimicrobial activities
Yousfi Tarek, Nationale Research for Biotechnology Research Center, Algeria
Title : Racial disparities in pediatric pneumonia in Brazil: The role of structural racism forging inequalities in acess to vaccines
Livia Daflon Silva, Federal University of State of Rio de Janeiro, Brazil
Title : Immunosuppression in COVID-19 Patients and Emerging Fungal Infections: Vaccines, Diagnosis and Strategies to Treat Comorbidities
K R Aneja, Kurukshetra University, India
Title : Immunogenicity and Cryo-EM structure of native-like HIV-1 Clade-C envelope trimers derived from a pediatric elite-neutralizer
Swarandeep Singh, All India Institute of Medical Sciences, India
Title : Why is the vaccine life-threatening if people get a fever after a COVID-19 vaccination
Yacob Mathai, Marma Health Centre, India
Title : Barriers to polio eradication in South Asia: A systematic review
Awranoos Ahadi, Bolan Medical College, Pakistan