Viral core proteins are essential components of a virus's structure, playing crucial roles in the viral life cycle. These proteins are typically located at the core or nucleocapsid of the virus and are involved in packaging and protecting the viral genome. One example is the capsid protein, which forms the protective outer shell of the virus. This protein is responsible for encapsulating and shielding the viral genetic material from the host cell's defenses. The capsid may have various shapes, such as icosahedral or helical, depending on the virus type. Another critical core protein is the nucleocapsid protein, which directly interacts with the viral genome, ensuring its proper condensation and organization. The nucleocapsid protein is crucial for genome replication, transcription, and packaging. In retroviruses like HIV, the core protein, p24, forms the viral capsid, protecting the viral RNA during its journey from the host cell entry to integration into the host genome. Understanding viral core proteins is fundamental for designing antiviral strategies, as disrupting these components can inhibit viral replication and assembly. Research in this area contributes to the development of antiviral drugs and vaccines aimed at targeting the core components of various viruses.
Title : A promising novel approach to DNA vaccines
Khursheed Nadeem Anwer, IMUNON, United States
Title : Nanoscopic SubATVax™ adjuvanted vaccines against influenza A types H3N2, H1N1 and influenza type B for subcutaneous administration
David Craig Wright, D4 Labs, LLC, United States
Title : The importance of post-marketing surveillance and real-world data for a product to be successful
Regina Au, BioMarketing Insight, United States
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : Commensal bacteria drive B-cell lymphomagenesis in the setting of innate immunodeficiency
Ping Xie, Rutgers University, United States
Title : The role of immunity in the pathogenesis of SARS-COV-2 and in the protection generated by COVID-19 in different age groups
Ahmed Abdulazeez, BHRUT Trust, United Kingdom
Title : Establishing a platform method for physical appearance assessment of new parenteral pharmaceuticals
Ying Wan, Merck & Co., United States
Title : Evaluating the immunogenic impact of process impurities in mRNA vaccine production: Establishing integrated control strategies and specifications
Jesse Kuiper, Merck Research Laboratories, United States
Title : New biomarkers in leishmania major vaccine development
Negar Seyed, Pasteur Institute of Iran, Iran (Islamic Republic of)
Title : Advances in vaccines: Revolutionizing disease prevention
Delia Teresa Sponza, Dokuz Eylul University, Turkey