Viral cell transformation is a complex phenomenon where certain viruses have the ability to alter the normal growth and behavior of host cells, leading to cellular transformation. This process is particularly associated with oncoviruses, viruses that can induce the formation of cancerous cells. During viral cell transformation, viral genes or proteins interfere with the host cell's regulatory mechanisms, promoting uncontrolled cell growth and evasion of normal cellular checkpoints. This can result in the formation of tumors and contribute to the development of various cancers. Examples of viruses associated with cell transformation include human papillomavirus (HPV), Epstein-Barr virus (EBV), and hepatitis B and C viruses. These viruses are implicated in cervical cancer, Burkitt's lymphoma, and hepatocellular carcinoma, respectively. Viral oncoproteins, such as the E6 and E7 proteins of HPV, can disrupt the functions of tumor suppressor proteins and promote genomic instability. Understanding the mechanisms of viral cell transformation is crucial for developing strategies to prevent and treat virus-induced cancers, highlighting the intersection of virology and cancer biology.
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Title : Tubercular disease in children: Optimizing treatment strategies through disease insights
Elena Chiappini, University of Florence, Italy
Title : Prophylactic and Molecular Approaches for Mitigating Human Influenza A Viruses: i. Evaluating influenza Vaccine Effectiveness in the Older population ii. Down-regulation of influenza virus genes with novel siRNA-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : The role of immunity in the pathogenesis of SARS-COV-2 and in the protection generated by COVID-19 in different age groups
Ahmed Abdulazeez, BHRUT Trust, United Kingdom
Title : Development of a Novel Multi-component Vaccine to Address the Burden of Otitis Media in High-Risk Populations
Ayesha Zahid, Griffith University, Australia
Title : Targeting resistance: New 4-substituted pyrazolidine and isoxazolidine as antibiotics with interesting antimicrobial activities
Yousfi Tarek, Nationale Research for Biotechnology Research Center, Algeria
Title : Racial disparities in pediatric pneumonia in Brazil: The role of structural racism forging inequalities in acess to vaccines
Livia Daflon Silva, Federal University of State of Rio de Janeiro, Brazil
Title : Immunosuppression in COVID-19 Patients and Emerging Fungal Infections: Vaccines, Diagnosis and Strategies to Treat Comorbidities
K R Aneja, Kurukshetra University, India
Title : Immunogenicity and Cryo-EM structure of native-like HIV-1 Clade-C envelope trimers derived from a pediatric elite-neutralizer
Swarandeep Singh, All India Institute of Medical Sciences, India
Title : Why is the vaccine life-threatening if people get a fever after a COVID-19 vaccination
Yacob Mathai, Marma Health Centre, India
Title : Barriers to polio eradication in South Asia: A systematic review
Awranoos Ahadi, Bolan Medical College, Pakistan