Vaccine technology encompasses a diverse array of innovative approaches aimed at developing safe, effective, and accessible vaccines to combat infectious diseases. Traditional vaccine technologies, including live attenuated and inactivated vaccines, have been complemented and expanded by cutting-edge methods. mRNA vaccines, exemplified by the COVID-19 vaccines from Pfizer-BioNTech and Moderna, represent a groundbreaking technology that utilizes genetic material to instruct cells to produce viral proteins and trigger an immune response. Viral vector vaccines, like those developed by AstraZeneca and Johnson & Johnson, use modified viruses to deliver genetic instructions, stimulating immune reactions. Advances in recombinant DNA technology enable the production of subunit vaccines, utilizing specific proteins or fragments of pathogens to elicit immune responses. Nanoparticle-based vaccines, adjuvants, and delivery systems contribute to enhancing immunogenicity and optimizing vaccine formulations. Gene editing tools, such as CRISPR, hold potential for targeted vaccine development, while platforms like virus-like particles (VLPs) mimic the structure of viruses without causing disease, providing a safe and effective alternative. As technology continues to evolve, ongoing research in vaccine technology strives to address emerging infectious threats, improve vaccine efficacy, and ensure global accessibility, ultimately contributing to the advancement of public health worldwide.
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : Homology analysis of MPXV and VACV peptides underscores the need to consider both MPXV clades for vaccine development
Lara Isis Teodoro, Mayo Clinic, United States
Title : Development of a novel multi-component vaccine to address the burden of otitis media in high-risk populations
Ayesha Zahid, Griffith University, Australia
Title : High seroprevalence of RSV antibodies in adults indicates potential undetected transmission and requires further public health assessment
Lara Isis Teodoro, Mayo Clinic, United States
Title : The role of immunity in the pathogenesis of SARS-COV-2 and in the protection generated by COVID-19 in different age groups
Ahmed Abdulazeez, BHRUT Trust, United Kingdom
Title : New biomarkers in leishmania major vaccine development
Negar Seyed, Pasteur Institute of Iran, Iran (Islamic Republic of)
Title : Tubercular disease in children: Optimizing treatment strategies through disease insights
Elena Chiappini, University of Florence, Italy
Title : Approaches towards developing and establishing a biomanufacturing research & development, and manufacturing industry in Zimbabwe: A review of the need, potential funding sources, policy development and implementation
Elliot Nyagumbo, Midlands State University, Zimbabwe
Title : Racial disparities in pediatric pneumonia in Brazil: The role of structural racism forging inequalities in acess to vaccines
Livia Daflon Silva, Federal University of State of Rio de Janeiro, Brazil
Title : Capillary electrophoresis for adjuvanted multivalent recombinant vaccine purity determination
Ashley Prout, Merck, United States