COVID-19 vaccines represent a groundbreaking achievement in the global response to the pandemic caused by the novel coronavirus, SARS-CoV-2. Multiple vaccines, developed using diverse technologies, have played a pivotal role in preventing severe illness, hospitalizations, and deaths associated with COVID-19. Messenger RNA (mRNA) vaccines, such as those developed by Pfizer-BioNTech and Moderna, introduce genetic instructions to cells, prompting the production of the virus's spike protein and eliciting a robust immune response. Viral vector vaccines, like those from AstraZeneca and Johnson & Johnson, use harmless adenoviruses to deliver genetic material, stimulating an immune reaction. These vaccines underwent rigorous testing in large-scale clinical trials, demonstrating high efficacy in preventing symptomatic COVID-19 and severe outcomes. Global vaccination campaigns aim to achieve widespread immunity, curb transmission, and mitigate the impact of the virus on public health. The rapid development and deployment of COVID-19 vaccines highlight the collaboration between scientists, governments, and pharmaceutical companies. Ongoing research focuses on vaccine effectiveness against emerging variants, booster doses, and addressing vaccine distribution challenges to ensure equitable access worldwide.
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : Homology analysis of MPXV and VACV peptides underscores the need to consider both MPXV clades for vaccine development
Lara Isis Teodoro, Mayo Clinic, United States
Title : High seroprevalence of RSV antibodies in adults indicates potential undetected transmission and requires further public health assessment
Lara Isis Teodoro, Mayo Clinic, United States
Title : A promising novel approach to DNA vaccines
Khursheed Anwer, IMUNON, United States
Title : The role of immunity in the pathogenesis of SARS-COV-2 and in the protection generated by COVID-19 in different age groups
Ahmed Abdulazeez, BHRUT Trust, United Kingdom
Title : Development of a novel multi-component vaccine to address the burden of otitis media in high-risk populations
Ayesha Zahid, Griffith University, Australia
Title : Tubercular disease in children: Optimizing treatment strategies through disease insights
Elena Chiappini, University of Florence, Italy
Title : New biomarkers in leishmania major vaccine development
Negar Seyed, Pasteur Institute of Iran, Iran (Islamic Republic of)
Title : Racial disparities in pediatric pneumonia in Brazil: The role of structural racism forging inequalities in acess to vaccines
Livia Daflon Silva, Federal University of State of Rio de Janeiro, Brazil
Title : Approaches towards developing and establishing a biomanufacturing research & development, and manufacturing industry in Zimbabwe: A review of the need, potential funding sources, policy development and implementation
Elliot Nyagumbo, Midlands State University, Zimbabwe