Vaccine production is a complex and highly regulated process involving multiple stages, from research and development to manufacturing and distribution. The primary goal is to produce safe, effective, and consistently high-quality vaccines to address various infectious diseases. The production process begins with the selection of the vaccine's target pathogen or antigen. Depending on the vaccine type, antigens may be derived from inactivated or attenuated pathogens, subunit proteins, or genetic material like DNA or mRNA. Large-scale manufacturing involves cultivating the chosen antigen in cell cultures, eggs, or bioreactors, followed by purification and formulation. Adjuvants and stabilizers are carefully added to enhance the vaccine's immunogenicity and stability. Quality control measures ensure the consistency, purity, and safety of each batch. Rigorous testing, including clinical trials, assesses the vaccine's safety and efficacy in diverse populations. Global distribution requires adherence to cold chain logistics to maintain vaccine potency. Collaboration between manufacturers, regulatory agencies, and international organizations is crucial for efficient vaccine production and distribution, ensuring widespread accessibility and contributing to global health initiatives. Advances in vaccine production technologies, such as cell-based and recombinant methods, continue to improve efficiency, scalability, and the overall impact of vaccination programs worldwide.
Title : A promising novel approach to DNA vaccines
Khursheed Anwer, IMUNON, United States
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : The importance of post-marketing surveillance and real-world data: For a product to be successful
Regina Au, BioMarketing Insight, United States
Title : Development of a novel multi-component vaccine to address the burden of otitis media in high-risk populations
Ayesha Zahid, Griffith University, Australia
Title : New biomarkers in leishmania major vaccine development
Negar Seyed, Pasteur Institute of Iran, Iran (Islamic Republic of)
Title : Approaches towards developing and establishing a biomanufacturing research & development, and manufacturing industry in Zimbabwe: A review of the need, potential funding sources, policy development and implementation
Elliot Nyagumbo, Midlands State University, Zimbabwe
Title : Evaluating the immunogenic impact of process impurities in mRNA vaccine production: Establishing integrated control strategies and specifications
Jesse Kuiper, Merck Research Laboratories, United States
Title : Capillary electrophoresis for adjuvanted multivalent recombinant vaccine purity determination
Ashley Prout, Merck, United States
Title : Hypersensitivity and anti-SARS-COV-2 vaccination: A retrospective study of the year 2021 at the University Hospital Center of Tours (France)
Faure Quentin, The Savoie Metropolitan Hospital Center, France
Title : Targeting resistance: New 4-substituted pyrazolidine and isoxazolidine as antibiotics with interesting antimicrobial activities
Yousfi Tarek, Nationale Research for Biotechnology Research Center, Algeria