The Tuberculosis (TB) vaccine, known as Bacillus Calmette-Guérin (BCG), is a live attenuated vaccine derived from a strain of Mycobacterium bovis. BCG vaccination is primarily administered in regions with a high prevalence of TB and is often given to infants. The BCG vaccine provides variable protection against severe forms of childhood TB, particularly meningitis and disseminated disease. However, its efficacy against pulmonary TB, the most common form, varies, and it does not prevent the primary infection. Diagnosing and treating active TB cases remain the primary strategies for TB control. BCG vaccination is not routinely recommended in countries with a low TB incidence but may be administered to individuals at high risk, such as healthcare workers or those in close contact with TB patients. Research continues to explore new TB vaccines that offer enhanced protection, especially against pulmonary TB. Global efforts focus on improving diagnostics, treatment, and vaccine strategies to achieve the World Health Organization's goal of eliminating TB as a public health threat by 2035.
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : Homology analysis of MPXV and VACV peptides underscores the need to consider both MPXV clades for vaccine development
Lara Isis Teodoro, Mayo Clinic, United States
Title : Development of a novel multi-component vaccine to address the burden of otitis media in high-risk populations
Ayesha Zahid, Griffith University, Australia
Title : High seroprevalence of RSV antibodies in adults indicates potential undetected transmission and requires further public health assessment
Lara Isis Teodoro, Mayo Clinic, United States
Title : The role of immunity in the pathogenesis of SARS-COV-2 and in the protection generated by COVID-19 in different age groups
Ahmed Abdulazeez, BHRUT Trust, United Kingdom
Title : New biomarkers in leishmania major vaccine development
Negar Seyed, Pasteur Institute of Iran, Iran (Islamic Republic of)
Title : Tubercular disease in children: Optimizing treatment strategies through disease insights
Elena Chiappini, University of Florence, Italy
Title : Approaches towards developing and establishing a biomanufacturing research & development, and manufacturing industry in Zimbabwe: A review of the need, potential funding sources, policy development and implementation
Elliot Nyagumbo, Midlands State University, Zimbabwe
Title : Racial disparities in pediatric pneumonia in Brazil: The role of structural racism forging inequalities in acess to vaccines
Livia Daflon Silva, Federal University of State of Rio de Janeiro, Brazil
Title : Capillary electrophoresis for adjuvanted multivalent recombinant vaccine purity determination
Ashley Prout, Merck, United States