Signal transduction pathways are crucial for the immune system's response to vaccines, as they regulate how immune cells detect and respond to foreign pathogens. When a vaccine is administered, it interacts with immune cells such as dendritic cells or macrophages, triggering these signaling pathways. These pathways, such as the NF-kB pathway or those involving Toll-like receptors (TLRs), help initiate the immune response by activating transcription factors that stimulate the production of cytokines and other immune signaling molecules. By understanding these pathways, vaccine developers can design vaccines that better regulate the immune response, ensuring a more robust defense. Optimizing these pathways can improve vaccine efficacy by increasing the strength of the immune response, enhancing the production of antibodies, and ensuring long-term immunity. Additionally, it allows researchers to develop vaccines that balance immune activation, minimizing adverse effects while maximizing protective immunity against pathogens.
Title : The importance of post-marketing surveillance and real-world data for a product to be successful
Regina Au, BioMarketing Insight, United States
Title : Nanoscopic SubATVax™ adjuvanted vaccines against influenza A types H3N2, H1N1 and influenza type B for subcutaneous administration
David Craig Wright, D4 Labs, LLC, United States
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : A promising novel approach to DNA vaccines
Khursheed Nadeem Anwer, IMUNON, United States
Title : The role of immunity in the pathogenesis of SARS-COV-2 and in the protection generated by COVID-19 in different age groups
Ahmed Abdulazeez, BHRUT Trust, United Kingdom
Title : Establishing a platform method for physical appearance assessment of new parenteral pharmaceuticals
Ying Wan, Merck & Co., United States
Title : Advances in vaccines: Revolutionizing disease prevention
Delia Teresa Sponza, Dokuz Eylul University, Turkey
Title : Overcoming biophysical characterization challenges of small antigens in dilute vaccine formulations
Eric Kemp, Merck & Co., United States
Title : Commensal bacteria drive B-cell lymphomagenesis in the setting of innate immunodeficiency
Ping Xie, Rutgers University, United States
Title : A combined LC-MS and immunoassay approach to characterize preservative-induced destabilization of human papillomavirus virus-like particles adsorbed to an aluminum-salt adjuvant
Ria T Caringal, University of Kansas, United States