Regulatory T-cells (Tregs) are a specialized subset of immune cells that help maintain immune system balance by preventing excessive or inappropriate immune responses. In the context of vaccines, Treg-targeted therapies aim to harness or modulate these cells to enhance the body’s tolerance to specific antigens, reduce the risk of autoimmunity, and manage immune responses more effectively. Vaccines designed to activate or manipulate Tregs are particularly promising in treating autoimmune diseases, chronic inflammatory conditions, and even certain types of cancer. By promoting immune tolerance, these vaccines can reduce the occurrence of unwanted immune attacks on the body's own tissues. Treg vaccines also hold potential in cancer immunotherapy, where they can help modulate the immune system to focus on attacking tumor cells without triggering damaging side effects. This novel approach is opening up new avenues in vaccinology, particularly for diseases that involve immune dysregulation.
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Title : Personalized and Precision Medicine (PPM) via biodesign-driven translational applications and upgraded business modeling to secure the human biosafety: The next-step vaccinomics of the future
Sergey V Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Title : The promise of nanotechnology in Personalized & Precision Medicine: Nano-driven precision vaccinomics of the future
Sergey V Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Title : Recombinant BCG vaccine as a potent anti tuberculosis vaccine candidate
Sajal Dey, BRIC-Centre for DNA Fingerprinting and Diagnostics, India
Title : Emerging nanovaccine strategies for enhanced immune targeting and vaccine performance
Aysel Sadayli, V.Y. Axundov Scientific-Research Institute of Medical Prophylaxis, Azerbaijan
Title : Advancing vaccine availability and equity in low-resource settings: Evidence from Awendo Sub-County, Kenya
Millicent Ochieng, Clinton Health Access Initiative, Kenya
Title : Reaching zero-dose children through adaptive immunization strategies in security-compromised areas of Zamfara State, Nigeria
Attahir Abubakar, Ahmadu Bello University, Nigeria
Title : From local pilots to national policy: Key issues and challenges in implementing nationwide HPV vaccination in China
Shenglan Tang, Duke Global Health Institute, United States