Regulatory T-cells (Tregs) are a specialized subset of immune cells that help maintain immune system balance by preventing excessive or inappropriate immune responses. In the context of vaccines, Treg-targeted therapies aim to harness or modulate these cells to enhance the body’s tolerance to specific antigens, reduce the risk of autoimmunity, and manage immune responses more effectively. Vaccines designed to activate or manipulate Tregs are particularly promising in treating autoimmune diseases, chronic inflammatory conditions, and even certain types of cancer. By promoting immune tolerance, these vaccines can reduce the occurrence of unwanted immune attacks on the body's own tissues. Treg vaccines also hold potential in cancer immunotherapy, where they can help modulate the immune system to focus on attacking tumor cells without triggering damaging side effects. This novel approach is opening up new avenues in vaccinology, particularly for diseases that involve immune dysregulation.
Title : The importance of post-marketing surveillance and real-world data: For a product to be successful
Regina Au, BioMarketing Insight, United States
Title : A promising novel approach to DNA vaccines
Khursheed Anwer, IMUNON, United States
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : Post COVID-19 syndrome is associated with sex and severity of first COVID-19 episode in Honduras
Manuel Antonio Sierra Santos, Central American Technological University, Honduras
Title : Homology analysis of MPXV and VACV peptides underscores the need to consider both MPXV clades for vaccine development
Lara Isis Teodoro, Mayo Clinic, United States
Title : Establishing a platform method for physical appearance assessment of new parenteral pharmaceuticals
Ying Wan, Merck & Co., United States
Title : Development of a novel multi-component vaccine to address the burden of otitis media in high-risk populations
Ayesha Zahid, Griffith University, Australia
Title : High seroprevalence of RSV antibodies in adults indicates potential undetected transmission and requires further public health assessment
Lara Isis Teodoro, Mayo Clinic, United States
Title : New biomarkers in leishmania major vaccine development
Negar Seyed, Pasteur Institute of Iran, Iran (Islamic Republic of)
Title : Development of a platform UPLC-CAD method for high-throughput lipid quantitation and characterization in novel mRNA LNPs
Janet Muzulu, Sanofi, United States