Regulatory T-cells (Tregs) are a specialized subset of immune cells that help maintain immune system balance by preventing excessive or inappropriate immune responses. In the context of vaccines, Treg-targeted therapies aim to harness or modulate these cells to enhance the body’s tolerance to specific antigens, reduce the risk of autoimmunity, and manage immune responses more effectively. Vaccines designed to activate or manipulate Tregs are particularly promising in treating autoimmune diseases, chronic inflammatory conditions, and even certain types of cancer. By promoting immune tolerance, these vaccines can reduce the occurrence of unwanted immune attacks on the body's own tissues. Treg vaccines also hold potential in cancer immunotherapy, where they can help modulate the immune system to focus on attacking tumor cells without triggering damaging side effects. This novel approach is opening up new avenues in vaccinology, particularly for diseases that involve immune dysregulation.
Title : A promising novel approach to DNA vaccines
Khursheed Nadeem Anwer, IMUNON, United States
Title : Nanoscopic SubATVax™ adjuvanted vaccines against influenza A types H3N2, H1N1 and influenza type B for subcutaneous administration
David Craig Wright, D4 Labs, LLC, United States
Title : The importance of post-marketing surveillance and real-world data for a product to be successful
Regina Au, BioMarketing Insight, United States
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : Commensal bacteria drive B-cell lymphomagenesis in the setting of innate immunodeficiency
Ping Xie, Rutgers University, United States
Title : The role of immunity in the pathogenesis of SARS-COV-2 and in the protection generated by COVID-19 in different age groups
Ahmed Abdulazeez, BHRUT Trust, United Kingdom
Title : Establishing a platform method for physical appearance assessment of new parenteral pharmaceuticals
Ying Wan, Merck & Co., United States
Title : Evaluating the immunogenic impact of process impurities in mRNA vaccine production: Establishing integrated control strategies and specifications
Jesse Kuiper, Merck Research Laboratories, United States
Title : New biomarkers in leishmania major vaccine development
Negar Seyed, Pasteur Institute of Iran, Iran (Islamic Republic of)
Title : Advances in vaccines: Revolutionizing disease prevention
Delia Teresa Sponza, Dokuz Eylul University, Turkey