Inactivated vaccines, also known as killed vaccines, are a type of vaccine that utilizes viruses or bacteria that have been neutralized or killed to stimulate an immune response without causing disease. These vaccines are produced by rendering the infectious agent nonfunctional through chemical or physical methods. The inactivated agents in the vaccine cannot replicate or cause infection, making them safe for use, particularly in individuals with weakened immune systems. Inactivated vaccines typically require booster doses to maintain immunity over time. Common examples of inactivated vaccines include the polio vaccine, hepatitis A vaccine, and the whole-cell pertussis component in some versions of the DTP (diphtheria, tetanus, and pertussis) vaccine. Influenza vaccines, both injectable and some nasal spray formulations, also utilize inactivated viruses. While inactivated vaccines provide effective protection, they may require adjuvants or additional components to enhance the immune response. Their safety profile and ability to be used in various populations contribute to their widespread use in vaccination programs globally, preventing a range of infectious diseases.
Title : The importance of post-marketing surveillance and real-world data: For a product to be successful
Regina Au, BioMarketing Insight, United States
Title : A promising novel approach to DNA vaccines
Khursheed Anwer, IMUNON, United States
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : Post COVID-19 syndrome is associated with sex and severity of first COVID-19 episode in Honduras
Manuel Antonio Sierra Santos, Central American Technological University, Honduras
Title : Homology analysis of MPXV and VACV peptides underscores the need to consider both MPXV clades for vaccine development
Lara Isis Teodoro, Mayo Clinic, United States
Title : Establishing a platform method for physical appearance assessment of new parenteral pharmaceuticals
Ying Wan, Merck & Co., United States
Title : Development of a novel multi-component vaccine to address the burden of otitis media in high-risk populations
Ayesha Zahid, Griffith University, Australia
Title : High seroprevalence of RSV antibodies in adults indicates potential undetected transmission and requires further public health assessment
Lara Isis Teodoro, Mayo Clinic, United States
Title : New biomarkers in leishmania major vaccine development
Negar Seyed, Pasteur Institute of Iran, Iran (Islamic Republic of)
Title : Development of a platform UPLC-CAD method for high-throughput lipid quantitation and characterization in novel mRNA LNPs
Janet Muzulu, Sanofi, United States