Immunology and Immunochemistry are two interconnected fields of study that play vital roles in understanding the immune system and the development of vaccines. Immunology focuses on the study of the immune system, including its structure, function, and response to pathogens, while immunochemistry delves into the chemical processes underlying immune reactions and interactions between antigens and antibodies. Vaccines harness the principles of immunology and immunochemistry to stimulate the body's immune response and provide protection against infectious diseases. They contain antigens derived from pathogens, such as viruses or bacteria, which trigger the immune system to recognize and mount a defensive response.
When a vaccine is administered, the antigens it contains are recognized by specialized cells of the immune system, such as dendritic cells and macrophages. These cells process the antigens and present them to other immune cells, known as T cells and B cells, which play key roles in coordinating the immune response. T cells, also known as T lymphocytes, help to orchestrate the immune response by recognizing and destroying infected cells and releasing signaling molecules called cytokines that regulate the activity of other immune cells. B cells, on the other hand, produce antibodies, proteins that specifically bind to and neutralize the antigens.
The interaction between antigens and antibodies is central to the immune response and is governed by the principles of immunochemistry. Antibodies, also known as immunoglobulins, are Y-shaped proteins produced by B cells that bind to specific antigens with high affinity. Vaccines can contain whole pathogens, live attenuated or inactivated pathogens, specific protein subunits or antigens derived from pathogens, or genetic material encoding viral antigens. Each type of vaccine elicits a different immune response and provides varying degrees of protection against the targeted disease.
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Madhu Khanna, University of Delhi, India
Title : The importance of post-marketing surveillance and real-world data: For a product to be successful
Regina Au, BioMarketing Insight, United States
Title : Development of a novel multi-component vaccine to address the burden of otitis media in high-risk populations
Ayesha Zahid, Griffith University, Australia
Title : New biomarkers in leishmania major vaccine development
Negar Seyed, Pasteur Institute of Iran, Iran (Islamic Republic of)
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Elliot Nyagumbo, Midlands State University, Zimbabwe
Title : Evaluating the immunogenic impact of process impurities in mRNA vaccine production: Establishing integrated control strategies and specifications
Jesse Kuiper, Merck Research Laboratories, United States
Title : Capillary electrophoresis for adjuvanted multivalent recombinant vaccine purity determination
Ashley Prout, Merck, United States
Title : Hypersensitivity and anti-SARS-COV-2 vaccination: A retrospective study of the year 2021 at the University Hospital Center of Tours (France)
Faure Quentin, The Savoie Metropolitan Hospital Center, France
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Yousfi Tarek, Nationale Research for Biotechnology Research Center, Algeria