Immunology and Immunochemistry are two interconnected fields of study that play vital roles in understanding the immune system and the development of vaccines. Immunology focuses on the study of the immune system, including its structure, function, and response to pathogens, while immunochemistry delves into the chemical processes underlying immune reactions and interactions between antigens and antibodies. Vaccines harness the principles of immunology and immunochemistry to stimulate the body's immune response and provide protection against infectious diseases. They contain antigens derived from pathogens, such as viruses or bacteria, which trigger the immune system to recognize and mount a defensive response.
When a vaccine is administered, the antigens it contains are recognized by specialized cells of the immune system, such as dendritic cells and macrophages. These cells process the antigens and present them to other immune cells, known as T cells and B cells, which play key roles in coordinating the immune response. T cells, also known as T lymphocytes, help to orchestrate the immune response by recognizing and destroying infected cells and releasing signaling molecules called cytokines that regulate the activity of other immune cells. B cells, on the other hand, produce antibodies, proteins that specifically bind to and neutralize the antigens.
The interaction between antigens and antibodies is central to the immune response and is governed by the principles of immunochemistry. Antibodies, also known as immunoglobulins, are Y-shaped proteins produced by B cells that bind to specific antigens with high affinity. Vaccines can contain whole pathogens, live attenuated or inactivated pathogens, specific protein subunits or antigens derived from pathogens, or genetic material encoding viral antigens. Each type of vaccine elicits a different immune response and provides varying degrees of protection against the targeted disease.
Title : A universal AI design framework and brokerage platform for democratised manufacturing of mRNA therapeutics
Duccio Medini, BioForge, United States
Title : Personalized and Precision Medicine (PPM) via biodesign-driven translational applications and upgraded business modeling to secure the human biosafety: The next-step vaccinomics of the future
Sergey V Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Title : Development of VSV-vector based vaccine against H5N1 avian influenza by targeting both H5N1 hemagglutinin and matrix protein 2
Zhujun Ao, University of Manitoba, Canada
Title : A novel responsive microneedle platform for reliable drug and vaccine delivery
Huanhuan Li, Queen’s University Belfast, United Kingdom
Title : Emerging nanovaccine strategies for enhanced immune targeting and vaccine performance
Aysel Sadayli, V.Y. Axundov Scientific-Research Institute of Medical Prophylaxis, Azerbaijan
Title : The promise of nanotechnology in Personalized & Precision Medicine: Nano-driven precision vaccinomics of the future
Sergey V Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Title : Reaching zero-dose children through adaptive immunization strategies in security-compromised areas of Zamfara State, Nigeria
Attahir Abubakar, Ahmadu Bello University, Nigeria
Title : Comparative efficacy of different H9N2 avian influenza virus inactivated vaccines using some commercially available adjuvants for superior control in broilers
Ayman H M El Deeb, Cairo University, Egypt
Title : Structure-based design and development of next-generation Respiratory Syncytial Virus (RSV) vaccine
Lei Chen, Yikang Biotech Suzhou Co., Ltd, China
Title : Unmasking urban immunization inequities: A cross-sectional LQAS analysis of zero-dose drivers in slum and non-slum settings of Uttar Pradesh, India
Ashish Kumar Maurya, John Snow India, India