Epitope prediction is a critical component of modern vaccine design, helping researchers identify the specific parts of a pathogen’s proteins that can trigger a strong immune response. By analyzing the structure of antigens, computational tools are employed to predict which epitopes—small fragments of the antigen recognized by immune cells—are most likely to induce immunity. This is especially important for designing vaccines for pathogens that have high variability, like influenza or HIV. Accurate epitope prediction can significantly improve the efficacy of a vaccine, ensuring that it targets the most relevant components of a pathogen. This strategy not only enhances the immune response but also reduces the chances of the pathogen escaping immune detection due to mutations. As vaccine technology evolves, epitope prediction plays an increasingly important role in designing vaccines that provide broad protection, are more cost-effective, and can be rapidly adapted to emerging infectious diseases.
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : Homology analysis of MPXV and VACV peptides underscores the need to consider both MPXV clades for vaccine development
Lara Isis Teodoro, Mayo Clinic, United States
Title : Development of a novel multi-component vaccine to address the burden of otitis media in high-risk populations
Ayesha Zahid, Griffith University, Australia
Title : High seroprevalence of RSV antibodies in adults indicates potential undetected transmission and requires further public health assessment
Lara Isis Teodoro, Mayo Clinic, United States
Title : The role of immunity in the pathogenesis of SARS-COV-2 and in the protection generated by COVID-19 in different age groups
Ahmed Abdulazeez, BHRUT Trust, United Kingdom
Title : New biomarkers in leishmania major vaccine development
Negar Seyed, Pasteur Institute of Iran, Iran (Islamic Republic of)
Title : Tubercular disease in children: Optimizing treatment strategies through disease insights
Elena Chiappini, University of Florence, Italy
Title : Approaches towards developing and establishing a biomanufacturing research & development, and manufacturing industry in Zimbabwe: A review of the need, potential funding sources, policy development and implementation
Elliot Nyagumbo, Midlands State University, Zimbabwe
Title : Racial disparities in pediatric pneumonia in Brazil: The role of structural racism forging inequalities in acess to vaccines
Livia Daflon Silva, Federal University of State of Rio de Janeiro, Brazil
Title : Capillary electrophoresis for adjuvanted multivalent recombinant vaccine purity determination
Ashley Prout, Merck, United States