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Dengue Fever Vaccine

Dengue fever vaccines have undergone significant development, with notable advancements in research and clinical trials. Dengue, caused by the Dengue virus transmitted through Aedes mosquitoes, poses a substantial global health threat, and the pursuit of an effective vaccine has been a priority. Among the prominent candidates is Dengvaxia (CYD-TDV) by Sanofi Pasteur, the first Dengue vaccine licensed in several countries. However, its usage is restricted to individuals with prior Dengue exposure due to concerns about potential increased severity in Dengue-naive individuals. Ongoing research focuses on developing vaccines that provide broad protection across multiple Dengue virus serotypes, addressing the challenges of incomplete immunity and the risk of severe Dengue in certain populations. Several promising candidates are in various stages of clinical evaluation, offering hope for a more widely applicable and efficacious Dengue vaccine in the future. As the field of Dengue vaccine development is dynamic, it is essential to stay informed about the latest advancements and regulatory approvals beyond my last update in January 2022.

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