Dengue fever vaccines have undergone significant development, with notable advancements in research and clinical trials. Dengue, caused by the Dengue virus transmitted through Aedes mosquitoes, poses a substantial global health threat, and the pursuit of an effective vaccine has been a priority. Among the prominent candidates is Dengvaxia (CYD-TDV) by Sanofi Pasteur, the first Dengue vaccine licensed in several countries. However, its usage is restricted to individuals with prior Dengue exposure due to concerns about potential increased severity in Dengue-naive individuals. Ongoing research focuses on developing vaccines that provide broad protection across multiple Dengue virus serotypes, addressing the challenges of incomplete immunity and the risk of severe Dengue in certain populations. Several promising candidates are in various stages of clinical evaluation, offering hope for a more widely applicable and efficacious Dengue vaccine in the future. As the field of Dengue vaccine development is dynamic, it is essential to stay informed about the latest advancements and regulatory approvals beyond my last update in January 2022.
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : Homology analysis of MPXV and VACV peptides underscores the need to consider both MPXV clades for vaccine development
Lara Isis Teodoro, Mayo Clinic, United States
Title : High seroprevalence of RSV antibodies in adults indicates potential undetected transmission and requires further public health assessment
Lara Isis Teodoro, Mayo Clinic, United States
Title : A promising novel approach to DNA vaccines
Khursheed Anwer, IMUNON, United States
Title : The role of immunity in the pathogenesis of SARS-COV-2 and in the protection generated by COVID-19 in different age groups
Ahmed Abdulazeez, BHRUT Trust, United Kingdom
Title : Development of a novel multi-component vaccine to address the burden of otitis media in high-risk populations
Ayesha Zahid, Griffith University, Australia
Title : Tubercular disease in children: Optimizing treatment strategies through disease insights
Elena Chiappini, University of Florence, Italy
Title : New biomarkers in leishmania major vaccine development
Negar Seyed, Pasteur Institute of Iran, Iran (Islamic Republic of)
Title : Racial disparities in pediatric pneumonia in Brazil: The role of structural racism forging inequalities in acess to vaccines
Livia Daflon Silva, Federal University of State of Rio de Janeiro, Brazil
Title : Approaches towards developing and establishing a biomanufacturing research & development, and manufacturing industry in Zimbabwe: A review of the need, potential funding sources, policy development and implementation
Elliot Nyagumbo, Midlands State University, Zimbabwe