Cytokine modulation is an emerging area of research in vaccine development that focuses on the role of cytokines in regulating the immune response. Cytokines are signaling molecules that help coordinate the immune system’s response to infection. By modulating cytokine levels, scientists can influence the strength, duration, and type of immune response generated by a vaccine. For example, certain cytokines can enhance the activation of T cells and B cells, leading to stronger and more long-lasting immunity. Conversely, controlling cytokine responses can also reduce the risk of unwanted side effects, such as excessive inflammation. The ability to finely tune cytokine signaling is critical for developing vaccines that are both effective and safe. This approach has been used in the design of adjuvants, substances added to vaccines to boost their effectiveness, as well as in developing therapeutic vaccines for diseases like cancer, where the immune system needs to be specifically activated to target tumor cells.
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : Homology analysis of MPXV and VACV peptides underscores the need to consider both MPXV clades for vaccine development
Lara Isis Teodoro, Mayo Clinic, United States
Title : Development of a novel multi-component vaccine to address the burden of otitis media in high-risk populations
Ayesha Zahid, Griffith University, Australia
Title : High seroprevalence of RSV antibodies in adults indicates potential undetected transmission and requires further public health assessment
Lara Isis Teodoro, Mayo Clinic, United States
Title : The role of immunity in the pathogenesis of SARS-COV-2 and in the protection generated by COVID-19 in different age groups
Ahmed Abdulazeez, BHRUT Trust, United Kingdom
Title : New biomarkers in leishmania major vaccine development
Negar Seyed, Pasteur Institute of Iran, Iran (Islamic Republic of)
Title : Tubercular disease in children: Optimizing treatment strategies through disease insights
Elena Chiappini, University of Florence, Italy
Title : Approaches towards developing and establishing a biomanufacturing research & development, and manufacturing industry in Zimbabwe: A review of the need, potential funding sources, policy development and implementation
Elliot Nyagumbo, Midlands State University, Zimbabwe
Title : Racial disparities in pediatric pneumonia in Brazil: The role of structural racism forging inequalities in acess to vaccines
Livia Daflon Silva, Federal University of State of Rio de Janeiro, Brazil
Title : Capillary electrophoresis for adjuvanted multivalent recombinant vaccine purity determination
Ashley Prout, Merck, United States