Catpox virus, also known as feline cowpox or cowpox virus, is a member of the Orthopoxvirus genus. While the natural host is believed to be rodents, cats can become infected, and humans may acquire the virus through direct or indirect contact with infected animals. The virus is related to vaccinia virus and variola virus, the causative agent of smallpox. Catpox virus infections in cats typically present with skin lesions, nodules, and ulcerations. Transmission to humans can result in localized skin lesions, resembling those caused by other poxviruses. However, catpox virus infections in humans are generally self-limiting and less severe than human cowpox infections. The virus is zoonotic, and infections are rare. Human cases often occur in individuals with close contact with infected animals, particularly veterinarians and pet owners. Prevention involves proper hygiene and avoiding contact with sick animals. While catpox virus infections are generally not a major public health concern, continued surveillance and understanding of zoonotic poxviruses contribute to overall infectious disease knowledge and management.
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