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Attenuated Vaccines

Attenuated vaccines are a type of vaccine that involves using weakened forms of live pathogens to stimulate an immune response without causing the disease. These vaccines are created by modifying the pathogen in a way that it loses its virulence or disease-causing ability while retaining its immunogenicity. The weakened pathogen in the vaccine can still replicate within the body, leading to a robust and long-lasting immune response. Common examples of attenuated vaccines include the measles, mumps, and rubella (MMR) vaccine, the oral polio vaccine (OPV), and the yellow fever vaccine. Attenuated vaccines often provide strong and durable immunity with just one or a few doses. While effective, attenuated vaccines may not be suitable for individuals with weakened immune systems, as the weakened pathogen could pose a risk. Additionally, careful handling and storage are crucial to maintaining the vaccine's viability. Despite these considerations, attenuated vaccines have played a pivotal role in preventing a range of infectious diseases, contributing significantly to global public health efforts.

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