Antigen mimicry in vaccine development leverages the concept of designing synthetic antigens or modifying existing ones to resemble those found on pathogens, triggering a protective immune response without exposing the body to the harmful agent. This method is valuable in creating vaccines for viruses or bacteria with complex surface structures or those that are difficult to target directly. By mimicking the appearance of the pathogen, these vaccines stimulate the production of antibodies that recognize and neutralize the actual pathogen upon future exposure. For instance, some vaccines use parts of the pathogen’s surface proteins, which are similar to the natural ones but modified to ensure safety. Antigen mimicry not only enhances the specificity of immune responses but also opens up possibilities for broad-spectrum vaccines that could protect against multiple strains or even species of pathogens, improving global vaccination strategies.
Duccio Medini
BioForge, United States
Jocelyn Jakubik
Apex Pathogen Solutions, United States
Sergey V Suchkov
N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Rosane Cuber Guimaraes
Bio-Manguinhos/ Fiocruz, Brazil
Zhujun Ao
University of Manitoba, Canada
Sergey V Suchkov
N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences, Russian Federation
Ashish Kumar Maurya
John Snow India, India
Sajal Dey
BRIC-Centre for DNA Fingerprinting and Diagnostics, India
Ayman H M El Deeb
Cairo University, EgyptSubmit your abstract Today
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Duccio Medini, BioForge, United States
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