Acellular vaccines represent a significant advancement in immunization, utilizing purified components of pathogens to induce an immune response without the need for whole live organisms. Unlike traditional vaccines that use weakened or inactivated microbes, acellular vaccines focus on specific components such as proteins or sugars that trigger protective immunity. These vaccines are designed to provide a safer alternative by minimizing the risk of adverse reactions associated with live vaccines. Pertussis (whooping cough) vaccines are prominent examples of acellular vaccines, consisting of purified pertussis toxin, filamentous hemagglutinin, pertactin, and fimbriae. Acellular vaccines have demonstrated effectiveness in preventing infectious diseases while reducing the likelihood of side effects. Their development has been crucial in enhancing vaccine safety, especially for vulnerable populations like infants. The modular nature of acellular vaccines allows for targeted immunity, offering protection against specific virulence factors.
Title : The importance of post-marketing surveillance and real-world data: For a product to be successful
Regina Au, BioMarketing Insight, United States
Title : A promising novel approach to DNA vaccines
Khursheed Anwer, IMUNON, United States
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : Homology analysis of MPXV and VACV peptides underscores the need to consider both MPXV clades for vaccine development
Lara Isis Teodoro, Mayo Clinic, United States
Title : Development of a platform UPLC-CAD method for high-throughput lipid quantitation and characterization in novel mRNA LNPs
Janet Muzulu, Sanofi, United States
Title : Commensal bacteria drive B-cell lymphomagenesis in the setting of innate immunodeficiency
Ping Xie, Rutgers University, United States
Title : High seroprevalence of RSV antibodies in adults indicates potential undetected transmission and requires further public health assessment
Lara Isis Teodoro, Mayo Clinic, United States
Title : Establishing a platform method for physical appearance assessment of new parenteral pharmaceuticals
Ying Wan, Merck & Co., United States
Title : Post COVID-19 syndrome is associated with sex and severity of first COVID-19 episode in Honduras
Manuel Antonio Sierra Santos, Central American Technological University, Honduras
Title : Evaluating the immunogenic impact of process impurities in mRNA vaccine production: Establishing integrated control strategies and specifications
Jesse Kuiper, Merck Research Laboratories, United States