Vaccine evaluation is a comprehensive process that assesses the safety, efficacy, and immunogenicity of vaccines before they are approved for widespread use. Clinical trials form the cornerstone of vaccine evaluation, involving rigorous testing in human populations to determine a vaccine's ability to prevent disease and its overall safety profile. Phase I trials typically focus on safety and immune response in a small group of volunteers, while Phase II trials expand to a larger cohort to further evaluate safety and efficacy. Phase III trials involve thousands of participants to confirm efficacy, monitor adverse effects, and gather data for regulatory approval. Post-marketing surveillance continues after approval to monitor long-term safety and assess real-world effectiveness. Vaccine evaluation also considers the vaccine's impact on public health, including its ability to reduce disease incidence and transmission within communities. Advanced statistical methods and epidemiological studies contribute to ongoing evaluation efforts, ensuring that vaccines meet stringent standards for safety and effectiveness. Continuous monitoring and refinement of evaluation processes contribute to the development of safer and more effective vaccines, addressing evolving public health needs.
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : Homology analysis of MPXV and VACV peptides underscores the need to consider both MPXV clades for vaccine development
Lara Isis Teodoro, Mayo Clinic, United States
Title : Development of a novel multi-component vaccine to address the burden of otitis media in high-risk populations
Ayesha Zahid, Griffith University, Australia
Title : High seroprevalence of RSV antibodies in adults indicates potential undetected transmission and requires further public health assessment
Lara Isis Teodoro, Mayo Clinic, United States
Title : The role of immunity in the pathogenesis of SARS-COV-2 and in the protection generated by COVID-19 in different age groups
Ahmed Abdulazeez, BHRUT Trust, United Kingdom
Title : New biomarkers in leishmania major vaccine development
Negar Seyed, Pasteur Institute of Iran, Iran (Islamic Republic of)
Title : Tubercular disease in children: Optimizing treatment strategies through disease insights
Elena Chiappini, University of Florence, Italy
Title : Approaches towards developing and establishing a biomanufacturing research & development, and manufacturing industry in Zimbabwe: A review of the need, potential funding sources, policy development and implementation
Elliot Nyagumbo, Midlands State University, Zimbabwe
Title : Racial disparities in pediatric pneumonia in Brazil: The role of structural racism forging inequalities in acess to vaccines
Livia Daflon Silva, Federal University of State of Rio de Janeiro, Brazil
Title : Capillary electrophoresis for adjuvanted multivalent recombinant vaccine purity determination
Ashley Prout, Merck, United States