Immunometabolism refers to the changes in the metabolic processes of immune cells in response to infection or vaccination. Vaccines can influence immunometabolic pathways to enhance the function and survival of immune cells, such as T cells, B cells, and macrophages, which are essential for combating infections. When a vaccine is administered, immune cells alter their metabolism to meet the increased energy demands of pathogen detection, antigen processing, and immune response activation. This includes shifts in glucose, lipid, and amino acid metabolism, which are critical for cell proliferation and cytokine production. By understanding and leveraging immunometabolism, scientists can design vaccines that optimize immune cell function, ensuring that the immune system is not only activated but also prepared to respond more efficiently in the future. This approach has the potential to improve vaccine outcomes, especially for diseases requiring a strong and sustained immune response.
Title : The importance of post-marketing surveillance and real-world data: For a product to be successful
Regina Au, BioMarketing Insight, United States
Title : A promising novel approach to DNA vaccines
Khursheed Anwer, IMUNON, United States
Title : Prophylactic and molecular approaches for mitigating human influenza A viruses: i. Evaluating influenza vaccine effectiveness in the older population ii. Down-regulation of influenza virus genes with novel sirna-chimeric-ribozyme constructs
Madhu Khanna, University of Delhi, India
Title : Homology analysis of MPXV and VACV peptides underscores the need to consider both MPXV clades for vaccine development
Lara Isis Teodoro, Mayo Clinic, United States
Title : Development of a platform UPLC-CAD method for high-throughput lipid quantitation and characterization in novel mRNA LNPs
Janet Muzulu, Sanofi, United States
Title : Commensal bacteria drive B-cell lymphomagenesis in the setting of innate immunodeficiency
Ping Xie, Rutgers University, United States
Title : High seroprevalence of RSV antibodies in adults indicates potential undetected transmission and requires further public health assessment
Lara Isis Teodoro, Mayo Clinic, United States
Title : Establishing a platform method for physical appearance assessment of new parenteral pharmaceuticals
Ying Wan, Merck & Co., United States
Title : Post COVID-19 syndrome is associated with sex and severity of first COVID-19 episode in Honduras
Manuel Antonio Sierra Santos, Central American Technological University, Honduras
Title : Evaluating the immunogenic impact of process impurities in mRNA vaccine production: Establishing integrated control strategies and specifications
Jesse Kuiper, Merck Research Laboratories, United States