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Endogenous Retrovirus

Endogenous retroviruses (ERVs) are remnants of ancient retroviral infections embedded in the genomes of host organisms. Arising from past viral invasions, ERVs have become integral components of the host's genetic material. While typically dormant, these viral elements can impact host functions and contribute to genetic diversity. Some ERVs have been repurposed for beneficial roles, such as influencing placental development. However, under certain conditions, ERVs may be reactivated and linked to diseases like cancer and autoimmune disorders. Studying ERVs provides insights into the evolutionary interplay between viruses and hosts, offering a fascinating perspective on genome dynamics and potential health implications.

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