Cross-reactive antibodies are a unique outcome of certain vaccines, as they allow for broader immunity by recognizing and neutralizing different pathogens beyond the original target. This cross-reactivity occurs when antibodies generated against one antigen are capable of binding to related, but distinct, antigens found in different strains or even species of pathogens. For example, cross-reactive antibodies in influenza vaccines can sometimes protect against multiple flu strains, providing broader coverage. While beneficial, cross-reactivity also presents challenges: there is a risk of non-specific immune responses, which may reduce vaccine efficacy or lead to off-target effects. Understanding and harnessing cross-reactivity is particularly valuable in vaccine design for rapidly mutating viruses, such as influenza and coronaviruses, as it holds potential for creating vaccines that provide immunity across multiple strains and emerging variants.
Khursheed Anwer
IMUNON, United States
Ping Xie
Rutgers University, United States
Regina Au
BioMarketing Insight, United States
Madhu Khanna
University of Delhi, India
Lara Isis Teodoro
Mayo Clinic, United States
Ahmed Abdulazeez
BHRUT Trust, United Kingdom
Elena Chiappini
University of Florence, Italy
Ayesha Zahid
Griffith University, Australia
Livia Daflon Silva
Federal University of State of Rio de Janeiro, Brazil
Neha Bhandari
Chitkara University, IndiaSubmit your abstract Today
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Madhu Khanna, University of Delhi, India
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