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Antigen-Presenting Cells in Vaccine Delivery

Antigen-presenting cells (APCs), such as dendritic cells and macrophages, are pivotal in initiating immune responses, making them vital targets in vaccine delivery. These cells capture and process antigens, presenting them to T-cells and triggering a specific immune response. In recent vaccine strategies, APCs are directly targeted or engineered to increase their ability to present antigens effectively, amplifying the immune reaction. Techniques such as nanoparticle-based delivery systems are used to direct antigens precisely to APCs, ensuring an efficient and potent immune activation. This targeted approach is especially beneficial in complex diseases where a robust immune response is essential, such as in cancer immunotherapy. By harnessing the power of APCs, vaccine developers create vaccines that induce stronger, more durable immunity, providing long-lasting protection.

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