Lung cancer is the first cause of death from cancer in the world and in some countries as the first cause of death for both sexes. Early diagnosis and timely therapy is successful for increasing the survival of these patients, however, the masking with frequent symptoms of other [....] » Read More
COVID-19 continues to be a global health problem, it is a multifactorial disease characterized by a process of hyperinflammation. Itolizumab, a humanized anti-CD6 mAb, has the Emergency Use Authorization (UEA) for patients with this disease with signs of hyperinflammation. Method [....] » Read More
The devastating novel coronavirus (COVID-19) pandemic worldwide has become a global health crisisThis disease is highly contagious and caused by the transmission of severe acute respiratory syndrome, coronavirus 2 (SARS-CoV-2). To prevent the transmission of SARS-CoV-2, disinfect [....] » Read More
The National Institute of Health recommends Nirmatrelvir-Ritonavir (NIR) treatment for pregnant patients with COVID-19. However, little is known about NIR treatment acceptance rates in pregnant patients and what strategies may increase access and acceptance rates of NIR treatment [....] » Read More
This study provides a mapping of funds contributed by different actors for the R&D and the expansion of the production capacity of COVID-19 vaccines, with a focus on those authorised in the EU. Nine vaccines are examined. It is found that governments, mainly the US (with some [....] » Read More
Immune senescence and inflammaging render older persons more susceptible to severe consequences of infectious diseases and likely to exhibit poorer responses to vaccination. Older persons need influenza, pneumococcal, herpes zoster, pertussis and SARS-CoV-2 vaccines and soo [....] » Read More
however ANA, rheumatoid factor Reactive arthritis after various vaccinations has been previously described but such kind of reaction after mpox vaccination has not been previously reported. Here we present a case of recently diagnosed reactive arthritis following intradermal mpox [....] » Read More
70% of people over 65 are hypertensive; high blood pressure increases the risk of exposure to cardiovascular disease (myocardial infarction and heart failure) and stroke. This is a public health problem, given the aging of the population. There are few studies carried out in e [....] » Read More
In the wake of the COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2), the global healthcare landscape has undergone a profound transformation. This transformation has been marked by the rapid development and deployment of COVID-19 vaccines [....] » Read More
Introduction In recent years, politics and business have become increasingly intertwined, with employees increasingly seeking workplaces that align with their political views (Stuckatz, 2020). The COVID-19 pandemic response introduced public health regulations that became cont [....] » Read More
Introduction: As the pandemic evolves and nations refocus on routine immunizations and vaccine-preventable outbreaks, it is critical to continue increasing vaccine demand. Misinformation threatens the success of vaccination programs across the world. Since 2017, The Public Good P [....] » Read More
It’s not just the bacteria or viruses that most commonly cause life-threatening disease in human, some of them could be fungal pathogens. Since 2013, the Leading International Fungal Education (LIFE) portal has facilitated the estimation of the burden of serious fungal infe [....] » Read More
One of the crucial steps in deploying plasma therapy for COVID-19 has been the development of critical assays to detect SARS-CoV-2 antibodies and evaluate their potential suitability. Unfortunately, assays that assess neutralizing antibodies involve use of live SARS-CoV-2 virus i [....] » Read More
The UK Health Security Agency (UKHSA) has longstanding expertise in the technological support of vaccine development through a vast array of immunological assays. In early 2020, using this valuable knowledge, scientists within UKHSA were able to rapidly develop a live virus micro [....] » Read More
Neonatal sepsis is a bloodstream infection that affects newborn infants under the age of 28 days and is a leading cause of morbidity and mortality in these children 1,2. There is little information on the prevalence of newborn sepsis, however Fleischmann-Struzek et al. estim [....] » Read More
The insecticide-treated mosquito net is one of the preventive tools in the fight against malaria vectors in the Republic of Congo. The general objective of this study was to assess the impact of the use of long-acting insecticide-treated mosquito nets in the strategy for the cont [....] » Read More
The use of low-energy electron irradiation (LEEI) is a novel and highly efficient method for manufacturing vaccines and other pharmaceutical products. This technology provides advantages against conventional methods for virus inactivation, as the process is faster, does not requi [....] » Read More
Viral fusion proteins enable cellular infection by fusing viral and cellular membranes accompanied by their transition from the pre-fusion to the post-fusion conformation during viral entry. Fusion proteins in their prefusion conformation elicit high neutralizing antibodies [....] » Read More
Viral fusion proteins enable cellular infection by fusing viral and cellular membranes accompanied by their transition from the pre-fusion to the post-fusion conformation during viral entry. Fusion proteins in their prefusion conformation elicit high neutralizing antibodies [....] » Read More
Recent advances in genomic and bioinformatic technologies have enabled the emergence of the field of immunogenomics. This intersection of immunology and genetics has expanded our understanding of how the immune system responds to infection and vaccination. While the immunogenetic [....] » Read More
Complete childhood vaccination remains poor in Sub-Saharan African countries. Although missed opportunity for vaccination (MOV) was found responsible for low coverage, median time-to-corrected is useful to assess delay in vaccination. MOV also reflects quality of immunization ser [....] » Read More
Title : Lessons learned from the Covid-19 vaccine and what is needed when developing a vaccine for a successful rollout
Regina Au, BioMarketing Insight, United States
When the COVID-19 Vaccine was developed, time was crucial and the pharmaceutical and biotechnology companies primary goal was to get a vaccine out as soon as possible so people to get vaccinated in saving lives. What wasn't considered which most large companies co [....] » Read More
Title : Why Low-Energy-Electron Irradiation might be a potential game changer for vaccine development, manufacturing, and pandemics prevention
Daniel Becker, KyooBe Tech GmbH, Germany
In the ongoing global Covid-19 aftermath, epidemics and pandemics triggered by microbial and viral pathogens remain a significant challenge for global vaccine production and worldwide supply. The Irradiation of target pathogens with low-energy electrons (LEEI) can reliably and [....] » Read More
Title : Medicinal synthetic aluminum-magnesium silicate {Al4 (SiO4)3 + 3Mg2SiO4?2Al2 Mg3 (SiO4)3} effective for: Viral diseases; Tumors; Antimicrobial resistant infections
Maduike Chiehiura Onwubiko Ezeibe, Michael Okpara University of Agriculture, Nigeria
Viral diseases, cancers (tumors) and antimicrobial resistant infections are among the world`s biggest health challenges. Literature reveals, that HIV and COVID-19 virus (RNA viruses) are positively charged while DNA viruses and abnormal (tumor/infected) cells are negatively charg [....] » Read More
Title : A DNA-based Vaccine Technology Independent of a Virus or Device
Khursheed Anwer, IMUNON, United States
This presentation describes the development of PLACCINE a novel DNA vaccine platform well-suited to overcome the limitations of the current vaccines. The PLACCINE platform leverages the inherent DNA advantages including design flexibility incorporating multi-antigen payload [....] » Read More
Title : System serology approach on COVID-19 patients’ sera reveal specific immune pattern in the heterogeneous population: The COVIDAuRA study
Levast Benoit, BIOASTER, France
The emergence of multiple SARS-CoV-2 variants as well as the implementation of different vaccination strategies gave rise to multiple immunization schemes in the population and related questions: which immunization strategy leads to the most effective long-term immune response ag [....] » Read More