HYBRID EVENT: You can participate in person at Baltimore, Maryland, USA or Virtually from your home or work.
Maryam Touhidinia, Speaker at Immunology Conferences
Yazd University, Iran (Islamic Republic of)
Title : Design of a multi-epitope vaccine using immunoinformatics approach


Immunoinformatics plays a key role in vaccine design and antibody production. In the past, antibody design and vaccine development are expensive and time-consuming. Nowadays, advances in the field of bioinformatics have provided practical tools that can be used to lessen the time and cost of vaccine and antibody design. The Immunoinformatics approach allows the identification of the immunogenic epitopes from the pathogen genomes. Also, the ideal and immunogenic parts could be developed as potential vaccine candidates to trigger protective immune responses in the hosts. In our studies, are identified the potential and immunogenic epitopes of a selected protein by bioinformatics tools. Then, these are selected based on allergenicity, antigenicity, and solubility features. And we use linkers and adjuvants to structure the epitope vaccines. Then, the 3D structure of the protein was predicted, and its affinity to different HLA, TLR was investigated by molecular docking. These methods have been performed with a wide range of bioinformatics tools to design vaccines against Covid19, Acinetobacter Baumannii, and Neisseria meningitidis. The design technique of these vaccines will be clearly mentioned in the lecture.


Maryam obtained a B.Sc. degree in Cellular and Molecular Biology from Yazd University in 2014. Then, she studied Masters of Molecular Genetics at the University of Yazd. He is now pursuing his research at the Department of Biology, Yazd University. Her special research interests focus on Bioinformatics, Microbiology, Structural Biology, Molecular Biology, and Biotechnology especially their application in recombinant vaccine research. In addition, her master's project was 'Isolation, cloning, expression of antigenic region of CarO gene from Acinetobacter baumannii'. Her recently project is the Design a multi-epitope vaccine against COVID-19. She is also an enthusiastic fan and an as new researcher in the field of monoclonal antibody design and drug design for different types of cancer and Covid19. She has published more than 20 research articles in journals and international congresses.