Laleh Yazdanpanah Goharrizi, Speaker at Therapeutic Vaccines Conferences
Agricultural Research Education and Extension Organization, Iran (Islamic Republic of)
Title : New technologies in shrimp and other crustacean vaccines

Abstract:

Researchers are looking for pathogens of shrimp without pathogens or SPF and shrimp tolerant to viral agents that are not pathogenic to humans and can only be pathogenic to shrimp and crustaceans. In 1998, a scientist stated that shrimp and insects could retain viruses for long periods of time without any adverse effects, proving that shrimp had not antibodies. Other research has shown that shrimp and insects can use DNA and RNA instead of antibodies to defend against viral pathogens. French scientists and researchers in the United States conducted research from 2013 to 2020 to prove that shrimp and insects copy viral RNA fragments into DNA and then insert DNA copies into their genomes. Finally, they block the translation into protein. A very surprising result on insects in France showed that fragments in viral RNA copied were seen in both linear and circular shapes, with very stable circular DNA, and the researchers showed that this DNA, which is Called CDVNA, it has the potential to be used as a viral vaccine in shrimp. Researchers are looking for ways to use antibiotics in aquaculture instead of boosting the immune system of invertebrates such as shrimp, especially with compatible safety. One of these measures is the development of a vaccine against shingles in shrimp. It is estimated that the Asian shrimp industry alone experienced an annual loss of 4 billion due to shrimp disease from 2009 to 2018. In one study, Dscam isoforms were detected in vaccinated and unvaccinated shrimp homocytes. Further analysis showed that LvDscam Ig2 and Ig3 regions are functionally important in shrimp-specific immune response against WSSV because it helps to identify specific pathogens. According to researchers on shrimp immunology, controlling vibriosis by vaccination is a promising option in the aquaculture industry. Therefore, researchers have used Vibrio pathogen-derived materials or whole inactivated Vibrio cells to stimulate the shrimp's immune system against Vibrio by focusing on the two commercial species P. vannamei and P. monodon. Various ways of vaccinating shrimp have been tried, one of which is oral administration through nutrition. It has also been done by injection into the cephalothorax, intramuscular injection and by immersion. Of course, the types of vaccinations are different. Formalin-killed, heat-killed, heat and formalin-killed, Vibrio bacterial cells isolated from biofilm, outer membrane protein, and lipopolysaccharide are used in vaccines against vibriosis in shrimps. Of course, maintaining proper hygiene practices regarding the use of safety stimulants may be a good approach to maintaining shrimp aquaculture worldwide.

Audience Take Away:

  • New technology of Shrimp vaccines would be considered and more explained
  • Importance of Vaccine role in Control and Prevention of Infectious diseases in Shrimp would be negotiated
  • Design of new vaccines and decreased of antibiotic resistance would be noticed

Biography:

Dr. Laleh Yazdanpanah Goharrizi started her university education in 1991 at the undergraduate level and in 2003, she received her master's degree. She also graduated with a doctorate in 2019 and received her degree from one of the prestigious Iranian universities in Kerman. She started working in the Fisheries Research Department at the Agricultural Research and Training Center in 1995.  She became a member of the faculty in 2003. She currently has 26 years of research experience and has several books, 140 conference papers, and lots numberof articles ISI and scientific research and extension papers, and is currently an assistant professor at the Fisheries Science Research Institute.

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