Title : A Novel Peptides Combination Carrying a New Hope for Treatment of HIV.
A novel mode of action for HIV assumes that production of neutralizing anti-HIV antibodies is the main cause in persisting the viral infection and its protection against destruction by the cytotoxic CD8+ T-cells. This novel postulation directed us to a new treatment formula termed V20E immune peptides combination comprising viral antigen particles and its non-specific Antibodies in oral and injectable form for inhibiting or preventing the disease. A controlled Randomized study was carried out on a total of twenty-one patients (17 males, 4 females; aged 20 38 years) all of them were positive for HIV antibodies and divided them into three groups (A), (B) and (C) each group contains seven patients and another group has only two patients As HIV-negative plasma and were enrolled on to a similar protocol and used them as control Group, we were classifying the first three groups according to their CD4+, CD8+T- cells and Viral load, all of them showed the same clinical symptoms of HIV/AIDS and wrote consent of Acceptance to take the V20E immune peptides combination therapy in the form of SC Injection or oral capsules for 12 weeks. At the end of therapy, all of the patient's viral loads Had reached under the detectable limits (less than 16 copies/ml); also, there were significant Increases of their CD4+ cells count over 45%. According to these findings, this therapeutic Modality was promising for treating HIV-1 disease and human immunodeficiency syndrome.
Audience take away:
HIV continues to be a major health problem world wide, however the situation is particularly serious in asia and africa countries, Therefore , the understanding of HIV mode of action and strategy will reduce more efforts , researches and can open the gate for a development of an effective vaccine or therapy that could help to reduce the severity of the disease and prevent the spreading of the infection. In this study we introduce a novel trail that differ from all the remedial previous trails , using the cellular and humoral immunity to induce a potent therapy and vaccine for curing and preventing HIV.