Zwile Zungu, Speaker at Vaccine Research Conference
University of Cape Town, South Africa
Title : Understanding SARS-CoV-2 vaccine hesitancy among pregnant women in Soweto, South Africa: A qualitative study

Abstract:

Introduction/Background: SARS-CoV-2 vaccine hesitancy among pregnant women in Soweto poses a significant public health concern, especially given the increased risk of COVID-19-related complications during pregnancy. Despite the availability of vaccines, uptake remains low across South Africa’s general population.

Material/Methods: This qualitative exploratory study utilized sixteen key informant interviews. These included pregnant women, health care workers, African traditional and faith healers, to examine the underlying factors affecting COVID-19 vaccine decisions among pregnant women in Soweto townships. Interviews were structured to uncover both motivations and perceived barriers to vaccine uptake.

Results: Findings revealed health-related concerns, financial incentives, and structural factors—such as employment, travel, and access to education—as primary motivators. Barriers included fear of side effects, needle aversion (with oral/nasal routes preferred), misinformation, limited health literacy, and distrust in the healthcare system and government institutions. Influential actors shaping vaccine decisions included family members, traditional healers, and healthcare professionals.

Discussion/Conclusion: The study highlights the multifaceted nature of vaccine hesitancy among pregnant women and underscores the importance of targeted health communication, community engagement, and alternative vaccine delivery strategies. Understanding these dynamics is vital for designing culturally sensitive and effective maternal vaccination campaigns.

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