Background: Paediatric tuberculosis (TB) represents a critical health concern due to the significant risk of extrapulmonary TB (EPTB), severe disease forms, and the increasing prevalence of drug-resistant strains (DR-TB). Understanding the clinical characteristics of affected chi [....] » Read More
If the body becomes inflamed after consuming a substance, our immune system tells us that the substance is against the body. If the substance further increases inflammation, reduces blood flow, and affects organ function, the substance is life-threatening. Vaccinat [....] » Read More
This study aims to review the available data regarding the central role of immunity in combating SARS-CoV-2 infection and in the generation of protection by vaccination against COVID-19 in different age groups. Physiologically, the immune response and the components involved in i [....] » Read More
Introduction: In Brazil, the 10-valent and 23-valent pneumococcal vaccines are available free of charge and are the most common pneumococcal vaccines administered. These vaccines play a key role in preventing severe bacterial infections caused by Streptococcus pneumoniae. However [....] » Read More
The incidence of fungal infections, called mycosis, has dramatically increased in COVID-19 patients with predisposing factors. COVID-19, not over and still circulating worldwide, is a respiratory illness caused by strains of coronavirus SARS-CoV-2 (severe acute respiratory syndro [....] » Read More
Title : Targeting resistance: New 4-substituted pyrazolidine and isoxazolidine as antibiotics with interesting antimicrobial activities
Yousfi Tarek, Nationale Research for Biotechnology Research Center, Algeria
A series of new isoxazolidine and pyrazolidine compounds were synthesized in very good yields of 76-99.2% by Michael and Aza-Michael reactions, respectively, and all compounds were characterized by 1H NMR, 13C NMR. we discovered that the pyrrolidine/benzoic acid catalyzed in Mich [....] » Read More
Title : Barriers to polio eradication in South Asia: A systematic review
Awranoos Ahadi, Bolan Medical College, Pakistan
Background: The Eastern Mediterranean Region (EMRO) of the World Health Organization (WHO) is the last region in which polio transmission continues. Afghanistan and Pakistan, also being parts of South Asia, pose a major burden for the transmission of the virus both in the EMRO an [....] » Read More
Title : Home-based HPV self-sampling assisted by a cloud-based electronic data system: Lessons learnt from a pilot community cervical cancer screening campaign in rural Ethiopia, May 2020
Temesgen Azemeraw Yitayew, Addis Ababa University, Ethiopia
Primary HPV testing and triage of HPV – positive women is an effective cervical cancer screening strategy. Such a multi-visit screening algorithm is also promising for community based screening in resource-poor communities, provided a robust tracking system is in place.&nbs [....] » Read More
Title : Awareness and Acceptability of Rotavirus Vaccine among mothers of under-five children in Gusau and Bungudu c Ommunities of Zamfara State, Northwestern Nigeria
Attahir Abubakar, Ahmadu Bello University , Nigeria
This study examines the awareness and acceptability of the rotavirus vaccine among mothers of children under five in Gusau and Bungudu, Zamfara State, Nigeria. Employing a comparative cross-sectional design, the research utilized quantitative surveys and qualitative focus groups [....] » Read More